Prevention of Hepatitis B Recurrence in Liver Transplant Patients Using Oral Antiviral Therapy without Long-Term Hepatitis B Immunoglobulin

prevention of hepatitis b recurrence in liver transplant patients using oral antiviral therapy without long-term hepatitis b immunoglobulin

Prevention of Hepatitis B Recurrence in Liver Transplant Patients Using Oral Antiviral Therapy without Long-Term Hepatitis B Immunoglobulin

BACKGROUND Small studies have suggested that nucleos(t)ide analogue therapy (NAT) with reduced hepatitis B immunoglobulin (HBIG) duration may be efficacious in preventing post-liver transplantation (LT) HBV recurrence. OBJECTIVES This larger study evaluates the use of NAT with short term (< 6 mo) or no HBIG for prevention of post-LT HBV recurrence. PATIENTS AND METHODS All HBV patients unde...

Surface protein mutations in chronic hepatitis B patients who received hepatitis B vaccine therapy

Objective (s):The aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis B surface antigen (HBsAg)-positive chronic hepatitis B virus (HBV) patients. Materials and Methods: 16 patients received the HBV vaccine and another 16 individuals from the control group did not. The surface gene was amplified and directly sequenced from samples...

Evolution of hepatitis B virus during long-term therapy in patients with chronic hepatitis B.

BACKGROUND Long-term lamivudine (LAM), adefovir (ADV) and entecavir (ETV) treatment induce the emergence of drug-resistant hepatitis B virus (HBV) in patients with chronic hepatitis B infection. AIM To evaluate the LAM, ADV and ETV resistance mutations detected in our patient group. MATERIALS AND METHODS Twenty patients who had received at least two years of treatment with nucleoside/tide a...

Hepatitis B Prevention and Immunization

هپاتیت به معنی التهاب کبد است. هپاتیت B هپاتیت سرمی هم نامیده می شود، ویروس آن از خون، مایعات سروزی بدن، بزاق و مایع منی یافت شده و باعث می گردد که سلولهای کبدی به دنبال واکنش التهابی عملکرد خود را از دست دهند که این حالت ممکن است منجر به انسداد مجاری صفراوی و یا نارسایی کبد شود.